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Structure of mammalian nalcn-FAM155A-UNC79-UNC80 quanternary complex

Analyse Structure of mammalian nalcn-FAM155A-UNC79-UNC80 quanternary complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7W7G
Type
protein
Length
4,758 residues
Chains
4
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
E5CYJ9, B8XCJ6, Q6Q760, Q8CCS2
Ligands
NAG, ZN

Structure

electron microscopy · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein1528—E5CYJ9
B—protein1711—B8XCJ6
C—protein1346—Q6Q760
D—protein173—Q8CCS2

Ligands and binding sites

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 3 copies · chains C, D
  • ZN · Zinc ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7W7G · Structure of Mammalian NALCN-FAM155A-UNC79-UNC80 quanternary complex · the same entry in another collection · chain A against A, TM-score 1.00
  • Q8CCS2 · AlphaFold monomer V2.0 prediction for transmembrane protein FAM155A (Q8CCS2) · a predicted model of the same protein · chain D against A, TM-score 0.96
  • Q6Q760 · AlphaFold monomer V2.0 prediction for sodium leak channel non- selective protein (Q6Q760) · a predicted model of the same protein · chain C against A, TM-score 0.95

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