Research workbench
Crystal structure of phenylalanine hydroxylase from bacillus cereus atcc 14579
Analyse Crystal structure of phenylalanine hydroxylase from bacillus cereus atcc 14579 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7VGM
- Type
- protein
- Length
- 571 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phenylalanine-4-hydroxylase
- EC
- 1.14.16.1
- UniProt
- Q818B4
- Ligands
- FE
- Pockets
- 5 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 45% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phenylalanine-4-hydroxylase (EC 1.14.16.1) | protein | 571 | 45% helix, 19% strand | Q818B4 |
Ligands and binding sites
- FE · Fe (III) ion · metal · chains A
- EDO · 1,2-ethanediol · additive · 7 copies · chains A
- ACY · Acetic acid · additive · 3 copies · chains A
- GOL · Glycerol · additive · 3 copies · chains A
- PEG · Di(hydroxyethyl)ether · additive · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1050 | 0.81 | 0.82 | 103 | ACY |
| 2 | 120 | 0.46 | 0.78 | 19 | empty |
| 3 | 78 | 0.32 | 0.74 | 23 | empty |
| 4 | 64 | 0.30 | 0.74 | 14 | PEG |
| 5 | 61 | 0.29 | 0.74 | 14 | PEG |
Compared structures
- 7VGM · Crystal structure of Phenylalanine hydroxylase from Bacillus cereus ATCC 14579 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q818B4
- Elsewhere: RCSB PDB 7VGM · PDBe 7VGM · UniProt Q818B4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.