Research workbench
Heparin-induced alpha-synuclein fibrils polymorph 4
Analyse Heparin-induced alpha-synuclein fibrils polymorph 4 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7V4C
- Type
- protein
- Length
- 186 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Alpha-synuclein
- UniProt
- P37840
- Pockets
- 1 · best druggability 0.32
Structure
electron microscopy · 1 distinct chain · 0% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| F, A, B | Alpha-synuclein | protein | 62 | 0% helix, 23% strand | P37840 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 99 | 0.32 | 0.72 | 29 | empty |
Interfaces
3 interfaces between chains.
- A–B · 2733 Ų buried · 66 hydrogen bonds · protein-protein
- F–A · 2726 Ų buried · 66 hydrogen bonds · protein-protein
- F–B · 411 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 7V4C · Heparin-induced alpha-synuclein fibrils polymorph 4 · the same entry in another collection · chain F against F, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P37840
- Elsewhere: RCSB PDB 7V4C · PDBe 7V4C · UniProt P37840
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.