Research workbench
Crystal structure of omsk hemorrhagic fever virus NS5 mtase (in complex with sah and gpppa)
Analyse Crystal structure of omsk hemorrhagic fever virus NS5 mtase (in complex with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7V1D
- Type
- protein
- Length
- 260 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Core protein
- EC
- 3.4.21.91, 3.6.1.15, 3.6.4.13
- UniProt
- C4TPE0
- Ligands
- SAH, G3A
- Pockets
- 1 · best druggability 0.66
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Core protein (EC 3.4.21.91, 3.6.1.15, 3.6.4.13) | protein | 260 | 37% helix, 18% strand | C4TPE0 |
Ligands and binding sites
- SAH · S-adenosyl-L-homocysteine · ligand · chains A
- G3A · Guanosine-P3-adenosine-5',5'-triphosphate · ligand · chains A
- GOL · Glycerol · additive · chains A
- IPA · Isopropyl alcohol · additive · chains A
- PEG · Di(hydroxyethyl)ether · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 559 | 0.66 | 0.77 | 56 | SAH |
Compared structures
- 7V1D · Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAH and… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C4TPE0
- Elsewhere: RCSB PDB 7V1D · PDBe 7V1D · UniProt C4TPE0
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