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Ligand · G3A

G3A · Guanosine-P3-adenosine-5',5'-triphosphate

G3A, Guanosine-P3-adenosine-5',5'-triphosphate (C20 H27 N10 O17 P3, 772.4 g/mol), in the MolNFT structures on GenesisL1: bound in 7 records (6 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and…

Component
G3A
Formula
C20 H27 N10 O17 P3
Class
ligand
Structures
7
PDB entries
6

Binding sites

G3A in 7 structures; the first of them:

  • 5C8S · Crystal structure of the SARS coronavirus nsp14-nsp10 complex with functional ligands SAH… · G3A B606 · binds VAL305, ASN306, CYS309, ARG310, GLN313, ASN334, LYS336, ILE338 and 10 more
  • 7V1D · Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAH and… · G3A A302 · binds LYS13, LEU16, ASN17, CYS19, LYS21, PHE24, ARG28, SER150 and 4 more
  • 8SWG · RNA duplex bound with GpppA dinucleotide ligand · G3A A101 · binds LCC1, LCC2, LCC3, G14
  • 8SWO · GpppA dinucleotide ligand binding to RNA UC template · G3A A101 · binds TLN1, LCC2, LCC3, G14
  • 8SX5 · GpppA dinucleotide binding to RNA CU template · G3A A101 · binds LCC1, TLN2, LCC3, G14
  • 5UDJ · IFIT1 monomeric mutant (L457E/L464E) with gppp-aaaa · G3A B1 · binds ARG38, GLN42, LEU46, THR48, TRP147, LEU150, LYS151, GLY154 and 11 more
  • 7V1D · Crystal structure of omsk hemorrhagic fever virus NS5 mtase (in complex with sah and… · G3A A302 · binds LYS13, LEU16, ASN17, CYS19, LYS21, PHE24, ARG28, SER150 and 3 more

Residues it binds most

LCC 6, ASN 5, LYS 5, PHE 5, ARG 5, G 6, SER 2, TYR 3, CYS 4, ILE 3 (residue and the binding sites it lines).

Found with

  • SAH · S-adenosyl-L-homocysteine
  • MG · Magnesium ion
  • GOL · Glycerol
  • IPA · Isopropyl alcohol
  • PEG · Di(hydroxyethyl)ether
  • CA · Calcium ion
  • ZN · Zinc ion
  • PGE · Triethylene glycol

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