Research workbench

Cryoem structure of the pancreatic ATP-sensitive potassium channel in the ATP-bound state with KIR6.2-ctd in the up conformation

Analyse Cryoem structure of the pancreatic ATP-sensitive potassium channel in the… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7UAA
Type: protein
Length: 2,753 residues
Chains: 5
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P70673, Q09427
Ligands: ATP

Structure

electron microscopy · 4 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	334	—	P70673
B, C	—	protein	330	—	P70673
D	—	protein	329	—	P70673
E	—	protein	1430	—	Q09427

Ligands and binding sites

ATP · Adenosine-5'-triphosphate · ligand · 5 copies · chains A, B, C, D, E

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7UAA · CryoEM structure of the pancreatic ATP-sensitive potassium channel in the ATP-bound state… · the same entry in another collection · chain E against E, TM-score 1.00
P70673 · AlphaFold monomer V2.0 prediction for ATP-sensitive inward rectifier potassium channel 11… · a predicted model of the same protein · chain D against A, TM-score 0.99
Q09427 · AlphaFold monomer V2.0 prediction for ATP-binding cassette sub-family C member 8 (Q09427) · a predicted model of the same protein · chain E against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P70673
Every structure of UniProt Q09427
Elsewhere: RCSB PDB 7UAA · PDBe 7UAA · UniProt P70673 · UniProt Q09427

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.