M379A mutant tyrosine phenol-lyase complexed with 3-bromo-dl- phenylalanine

Structure

x-ray diffraction · 1 distinct chain.

Ligands and binding sites

• PLP · Pyridoxal-5'-phosphate · ligand · 3 copies · chains B, C, D
• OY3 · (4Z)-4-({[(1E)-2-(3-bromophenyl)-1-carboxyethylidene]azaniumyl}methylidene)-2-methyl-5-[(phosphonooxy)methyl]-1,4-dihydropyridin-3-olate · ligand · 2 copies · chains A, B
• K · Potassium ion · metal · 4 copies · chains A, B, C, D
• CL · Chloride ion · ion · 3 copies · chains A, B, C, D
• DMS · Dimethyl sulfoxide · additive · 4 copies · chains A, B, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 7TDL · M379A mutant tyrosine phenol-lyase complexed with 3-bromo-DL-phenylalanine · the same entry in another collection · chain A against A, TM-score 1.00
• P31013 · AlphaFold monomer V2.0 prediction for tyrosine phenol-lyase (P31013) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P31013
• Elsewhere: RCSB PDB 7TDL · PDBe 7TDL · UniProt P31013