Research workbench
E. COLI dihydroorotate dehydrogenase bound to the inhibitor hmnq
Analyse E. COLI dihydroorotate dehydrogenase bound to the inhibitor hmnq in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7T5Y
- Type
- protein
- Length
- 671 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P0A7E1
- Ligands
- F2D, ORO, FMN, PO4
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 336 | — | P0A7E1 |
| B | — | protein | 335 | — | P0A7E1 |
Ligands and binding sites
- F2D · 3-methyl-2-[(2E)-non-2-en-1-yl]quinolin-4(1H)-one · ligand · 2 copies · chains A, B
- ORO · Orotic acid · ligand · 2 copies · chains A, B
- FMN · Flavin mononucleotide · ligand · 2 copies · chains A, B
- PO4 · Phosphate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7T5Y · E. coli dihydroorotate dehydrogenase bound to the inhibitor HMNQ · the same entry in another collection · chain A against A, TM-score 1.00
- P0A7E1 · AlphaFold monomer V2.0 prediction for dihydroorotate dehydrogenase (quinone) (P0A7E1) · a predicted model of the same protein · chain B against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A7E1
- Elsewhere: RCSB PDB 7T5Y · PDBe 7T5Y · UniProt P0A7E1
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