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Cryoem structure of the hcmv pentamer GH/GL/UL128/UL130/UL131A in complex with thbd and neutralizing fabs msl-109 and 13H11

Analyse Cryoem structure of the hcmv pentamer GH/GL/UL128/UL130/UL131A in complex with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7T4R
Type
protein
Length
3,595 residues
Chains
19
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P07204, F5H9T3, Q71DN9, Q38LY2, Q38M07, Q8AZ45
Ligands
NAG

Structure

electron microscopy · 15 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein144—P07204
B—protein630—F5H9T3
C—protein233—Q71DN9
D—protein129—Q38LY2
E—protein163—Q38M07
F—protein109—Q8AZ45
G, P—protein120——
H, Q—protein104——
I, R—protein111——
J, S—protein127——
K—protein633—F5H9T3
L—protein230—Q71DN9
M—protein132—Q38LY2
N—protein163—Q38M07
O—protein105—Q8AZ45

Ligands and binding sites

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 14 copies · chains B, C, E, F, K, N, M, O

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7T4R · CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with THBD and… · the same entry in another collection · chain S against S, TM-score 1.00

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