Research workbench

NADPH-dependent cytochrome P450 reductase 2B from sorghum bicolor (SBCPR2B)

Analyse NADPH-dependent cytochrome P450 reductase 2B from sorghum bicolor (SBCPR2B) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7SUZ
Type: protein
Length: 389 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: NADPH--cytochrome P450 reductase
EC: 1.6.2.4
UniProt: C5YJG8
Ligands: FAD
Pockets: 2 · best druggability 0.68

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	NADPH--cytochrome P450 reductase (EC 1.6.2.4)	protein	389	38% helix, 20% strand	C5YJG8

Ligands and binding sites

FAD · Flavin-adenine dinucleotide · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	580	0.68	0.77	55	FAD
2	68	0.44	0.82	16	empty

Compared structures

7SUZ · NADPH-dependent cytochrome P450 reductase 2b from Sorghum bicolor (SbCPR2b) · the same entry in another collection · chain A against A, TM-score 1.00
C5YJG8 · AlphaFold monomer V2.0 prediction for NADPH--cytochrome P450 reductase (C5YJG8) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt C5YJG8
Elsewhere: RCSB PDB 7SUZ · PDBe 7SUZ · UniProt C5YJG8

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