Research workbench
Apoferritin structure at 1.27 ångström resolution determined from a 300 kv titan krios G3I electron microscope with FALCON4 detector
Analyse Apoferritin structure at 1.27 ångström resolution determined from a 300 kv… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7RRP
- Type
- protein
- Length
- 4,128 residues
- Chains
- 24
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ferritin heavy chain
- EC
- 1.16.3.1
- UniProt
- P02794
- Ligands
- ZN, NA
- Pockets
- 20 · best druggability 0.77
Structure
electron microscopy · 1 distinct chain · 73% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | Ferritin heavy chain (EC 1.16.3.1) | protein | 172 | 73% helix, 1% strand | P02794 |
Ligands and binding sites
- ZN · Zinc ion · metal · 206 copies · chains A, S, E, F, T, I, M, B, R, P, V, L, C, U, O, G, K, D, J, X, Q, H, W, N
- NA · Sodium ion · metal · 72 copies · chains A, F, B, S, C, P, D, U, E, J, T, G, H, X, I, N, Q, K, L, W, M, R, O, V
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 76 | 0.77 | 0.99 | 15 | empty |
| 2 | 72 | 0.77 | 1.00 | 15 | empty |
| 3 | 73 | 0.77 | 0.99 | 15 | empty |
| 4 | 75 | 0.77 | 0.99 | 15 | empty |
| 5 | 75 | 0.77 | 0.99 | 16 | empty |
Interfaces
72 interfaces between chains.
- C–U · 1551 Ų buried · 27 hydrogen bonds · protein-protein
- I–Q · 1551 Ų buried · 27 hydrogen bonds · protein-protein
- A–S · 1549 Ų buried · 27 hydrogen bonds · protein-protein
- K–W · 1549 Ų buried · 27 hydrogen bonds · protein-protein
- D–F · 1549 Ų buried · 27 hydrogen bonds · protein-protein
Compared structures
- 7RRP · Apoferritin structure at 1.27 angstrom resolution determined from a 300 kV Titan Krios… · the same entry in another collection · chain J against J, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02794
- Elsewhere: RCSB PDB 7RRP · PDBe 7RRP · UniProt P02794
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.