Research workbench
In vitro assembled 266-391 tau filaments in pbs (23A)
Analyse In vitro assembled 266-391 tau filaments in pbs (23A) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7QL1
- Type
- protein
- Length
- 219 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Microtubule-associated protein tau
- UniProt
- P10636
- Pockets
- 1 · best druggability 0.52
Structure
electron microscopy · 1 distinct chain · 0% helix, 49% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C, D | Microtubule-associated protein tau | protein | 73 | 0% helix, 49% strand | P10636 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 138 | 0.52 | 0.79 | 22 | empty |
Interfaces
3 interfaces between chains.
- C–D · 3087 Ų buried · 75 hydrogen bonds · protein-protein
- A–D · 3081 Ų buried · 76 hydrogen bonds · protein-protein
- A–C · 31 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 7QL1 · In vitro assembled 266-391 tau filaments in PBS (23a) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P10636
- Elsewhere: RCSB PDB 7QL1 · PDBe 7QL1 · UniProt P10636
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