UniProt P10636
Microtubule-associated protein tau (P10636)
Microtubule-associated protein tau (UniProt P10636): 158 experimental structures on GenesisL1, 5 ligands bound, 112 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P10636
- Protein
- Microtubule-associated protein tau
- Experimental structures
- 158
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 112 · 27 records with a druggable one
Structures
158 records of P10636 in the MolNFT archive: 158 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1I8H | Solution structure of PIN1 ww domain complexed with human tau phosphothreonine peptide | solution nmr | A | — | — |
| 1I8H | Solution structure of PIN1 ww domain complexed with human tau phosphothreonine peptide | solution nmr | A | — | — |
| 2MZ7 | Structure of Tau(267-312) bound to Microtubules | solution nmr | A | — | — |
| 2MZ7 | Structure of TAU(267-312) bound to microtubules | solution nmr | A | — | — |
| 3OVL | Structure of an amyloid forming peptide VQIVYK from the TAU protein in complex with orange G | x-ray diffraction | A | — | — |
| 3OVL | Structure of an amyloid forming peptide vqivyk from the tau protein in complex with orange G | x-ray diffraction | A | — | — |
| 4FL5 | Crystal structure of human 14-3-3 sigma in complex with a Tau-protein peptide surrounding pS214 | x-ray diffraction | P, Q | — | — |
| 4FL5 | Crystal structure of human 14-3-3 sigma in complex with a tau-protein peptide surrounding PS214 | x-ray diffraction | P, Q | — | — |
| 4NP8 | Structure of an amyloid forming peptide VQIVYK from the second repeat region of tau (alternate… | x-ray diffraction | A | — | — |
| 4NP8 | Structure of an amyloid forming peptide vqivyk from the second repeat region of tau (alternate… | x-ray diffraction | A | — | — |
| 4TQE | Structure of tau peptide in complex with Tau5 antibody Fab fragment | x-ray diffraction | A | — | — |
| 4TQE | Structure of tau peptide in complex with TAU5 antibody Fab fragment | x-ray diffraction | A | — | — |
| 4Y5I | Crystal structure of C-terminal modified Tau peptide-hybrid 126B with 14-3-3sigma | x-ray diffraction | F, G | — | — |
| 4Y5I | Crystal structure of C-terminal modified tau peptide-hybrid 126B with 14-3-3SIGMA | x-ray diffraction | F, G | — | — |
| 5MO3 | Crystal structure of DC8E8 Fab in the complex with a 14-mer tau peptide at pH 8.5 | x-ray diffraction | A | — | — |
| 5MP1 | Crystal structure of DC8E8 Fab in the complex with a 14-mer tau peptide at pH 7.5 | x-ray diffraction | A, B, E, I | — | — |
| 5MP5 | Crystal structure of DC8E8 Fab in the complex with a 14-mer tau peptide at pH 6.5 | x-ray diffraction | I, J, K | — | — |
| 5N5A | Structure of TAU(254-290) bound to F-actin | solution nmr | A | — | — |
| 5N5B | Structure of Tau(292-319) bound to F-actin | solution nmr | A | — | — |
| 5N5B | Structure of TAU(292-319) bound to F-actin | solution nmr | A | — | — |
| 5O3L | Paired helical filament in ALZHEIMER'S disease brain | electron microscopy | A, B, C, D, E, F, G, H, I, J | — | — |
| 5O3O | Pronase-treated paired helical filament in Alzheimer's disease brain | electron microscopy | A, B, C, D, E, F, G, H, I, J | — | 6 (best 0.39) |
| 5O3O | Pronase-treated paired helical filament in ALZHEIMER'S disease brain | electron microscopy | A, B, C, D, E, F, G, H, I, J | — | — |
| 5O3T | Straight filament in Alzheimer's disease brain | electron microscopy | A, B, C, D, E, F, G, H, I, J | — | 5 (best 0.68) |
| 5O3T | Straight filament in ALZHEIMER'S disease brain | electron microscopy | A, B, C, D, E, F, G, H, I, J | — | — |
| 5V5B | Kvqiinkkld, structure of the amyloid spine from microtubule associated protein tau repeat 2 | electron crystallography | A | — | — |
| 5ZV3 | Crystal structure of human anti-tau antibody CBTAU-28.1 in complex with its tau peptide | x-ray diffraction | A | — | — |
| 5ZV3 | Crystal structure of human anti-tau antibody cbtau-28.1 in complex with its tau peptide | x-ray diffraction | A | — | — |
| 6BB4 | FAB/EPITOPE complex of mouse monoclonal antibody C5.2 targeting a phospho-tau epitope. | x-ray diffraction | P, Q, R | — | — |
| 6DC8 | FAB/EPITOPE complex of mouse monoclonal antibody 8B2 targeting a non- phosphorylated tau epitope. | x-ray diffraction | P | NH2, PO4 | — |
| 6DC9 | FAB/EPITOPE complex of human chimeric monoclonal antibody H4E6 targeting a phosphorylated tau… | x-ray diffraction | P, Q | PO4 | — |
| 6DCA | Fab/epitope complex of mouse monoclonal antibody 6B2 targeting a non-phosphorylated tau epitope. | x-ray diffraction | P, Q, R, S | PO4 | — |
| 6DCA | FAB/EPITOPE complex of mouse monoclonal antibody 6B2 targeting a non- phosphorylated tau epitope. | x-ray diffraction | P, Q, R, S | NH2, PO4 | — |
| 6GX5 | Narrow Pick Filament from Pick's disease brain | electron microscopy | A, B, C | — | — |
| 6GX5 | Narrow pick filament from PICK'S disease brain | electron microscopy | A, B, C | — | — |
| 6H06 | Fab cbtau-22.1 in complex with tau peptide V1088-5 | x-ray diffraction | I, G, J, K | — | — |
| 6HRE | Paired helical filament from sporadic Alzheimer's disease brain | electron microscopy | A, B, C, D, E, F | — | — |
| 6HRE | Paired helical filament from sporadic ALZHEIMER'S disease brain | electron microscopy | A, B, C, D, E, F | — | — |
| 6HRF | Straight filament from sporadic Alzheimer's disease brain | electron microscopy | A, B, C, D, E, F | — | — |
| 6HRF | Straight filament from sporadic ALZHEIMER'S disease brain | electron microscopy | A, B, C, D, E, F | — | — |
| 6N4P | Rqefev, crystal structure of the N-terminal segment rqefev from protein tau | x-ray diffraction | A, C | — | — |
| 6NK4 | Kvqiinkkl, crystal structure of a tau protein fragment | electron crystallography | A | — | — |
| 6NWP | Chronic traumatic encephalopathy Type I Tau filament | electron microscopy | A, B, C, D, E, F | — | — |
| 6NWP | Chronic traumatic encephalopathy type I tau filament | electron microscopy | A, B, C, D, E, F | — | — |
| 6NWQ | Chronic traumatic encephalopathy Type II Tau filament | electron microscopy | A, B, C, D, E, F | — | — |
| 6NWQ | Chronic traumatic encephalopathy type II tau filament | electron microscopy | A, B, C, D, E, F | — | — |
| 6ODG | SVQIVY, Crystal Structure of a tau protein fragment | x-ray diffraction | A, B | — | — |
| 6ODG | Svqivy, crystal structure of a tau protein fragment | x-ray diffraction | A, B | — | — |
| 6PXR | Anti-tau BIIB092 Fab with tau peptide | x-ray diffraction | A | — | — |
| 6QJH | Cryo-EM structure of heparin-induced 2N4R tau snake filaments | electron microscopy | A, C, B | — | — |
| 6QJH | Cryo-EM structure of heparin-induced 2N4R tau snake filaments | electron microscopy | A, C, B | — | — |
| 6QJM | Cryo-EM structure of heparin-induced 2N4R tau twister filaments | electron microscopy | A, B, C | — | — |
| 6QJP | Cryo-EM structure of heparin-induced 2N4R tau jagged filaments | electron microscopy | A, C, B | — | — |
| 6QJP | Cryo-EM structure of heparin-induced 2N4R tau jagged filaments | electron microscopy | A, C, B | — | — |
| 6QJQ | Cryo-EM structure of heparin-induced 2N3R tau filaments | electron microscopy | A, B, C, D, E, F | — | — |
| 6TJO | Cryo-EM structure of TypeI tau filaments extracted from the brains of individuals with Corticobasal… | electron microscopy | A, B, C | — | 5 (best 0.53) |
| 6TJO | Cryo-EM structure of typei tau filaments extracted from the brains of individuals with corticobasal… | electron microscopy | A, B, C | — | — |
| 6TJX | Cryo-EM structure of typeii tau filaments extracted from the brains of individuals with… | electron microscopy | A, B, C, D, E, F | — | — |
| 6VH7 | Doublet tau fibril from corticobasal degeneration human brain tissue | electron microscopy | A, B, C, E, F, G | — | — |
| 6VHA | Singlet tau fibril from corticobasal degeneration human brain tissue | electron microscopy | E, F, G | — | — |
98 records more on the page itself.
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