Research workbench
In vitro assembled 258-391 tau filaments with phosphoglycerate, 700 rpm (39A)
Analyse In vitro assembled 258-391 tau filaments with phosphoglycerate, 700 rpm (39A) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7QKG
- Type
- protein
- Length
- 162 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Microtubule-associated protein tau
- UniProt
- P10636
- Pockets
- 2 · best druggability 0.43
Structure
electron microscopy · 1 distinct chain · 0% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B, A, C | Microtubule-associated protein tau | protein | 54 | 0% helix, 48% strand | P10636 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 87 | 0.43 | 0.79 | 15 | empty |
| 2 | 53 | 0.33 | 0.78 | 22 | empty |
Interfaces
3 interfaces between chains.
- B–C · 2455 Ų buried · 67 hydrogen bonds · protein-protein
- B–A · 2450 Ų buried · 62 hydrogen bonds · protein-protein
- A–C · 279 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 7QKG · In vitro assembled 258-391 tau filaments with phosphoglycerate, 700 rpm (39a) · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P10636
- Elsewhere: RCSB PDB 7QKG · PDBe 7QKG · UniProt P10636
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