Crystal structure of phosphatidyl serine synthase (pss) in transition state.

Structure

x-ray diffraction · 2 distinct chains.

Ligands and binding sites

• SMW · (2S)-2-amino-3-[[[(2R,3S,4R,5R)-5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-[(2R)-2,3-bis[[(Z)-octadec-9-enoyl]oxy]propoxy]-dihydroxy-lambda^5-phosphanyl]oxy-propanoic acid · ligand · chains A
• 58A · 5'-O-[(R)-{[(S)-{(2R)-2,3-bis[(9e)-octadec-9-enoyloxy]propoxy}(hydroxy)phosphoryl]oxy}(hydroxy) phosphoryl]cytidine · ligand · chains B
• CA · Calcium ion · metal · 2 copies · chains A, B
• MG · Magnesium ion · metal · 2 copies · chains A, B
• CL · Chloride ion · ion · 6 copies · chains A, B
• OLC · (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate · additive · 10 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 7POW · Crystal structure of phosphatidyl serine synthase (PSS) in transition state. · the same entry in another collection · chain A against A, TM-score 1.00
• Q58609 · AlphaFold monomer V2.0 prediction for cdp-diacylglycerol--serine… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q58609
• Elsewhere: RCSB PDB 7POW · PDBe 7POW · UniProt Q58609