Research workbench

Crystal structure of bovine brain ca++ calmodulin in a compact form

Analyse Crystal structure of bovine brain ca++ calmodulin in a compact form in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1PRW
Type: protein
Length: 148 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Calmodulin
UniProt: P62157
Ligands: ACE, CA
Pockets: 2 · best druggability 0.86

Structure

x-ray diffraction · 1 distinct chain · 58% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Calmodulin	protein	148	58% helix, 4% strand	P62157

Ligands and binding sites

ACE · Acetyl group · ligand · chains A
CA · Calcium ion · metal · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	320	0.86	0.95	34	empty
2	108	0.40	0.76	18	empty

Modifications

Observed in the structure: 1 covalent, 1 modified (covalent ligand, methylation).

Compared structures

1PRW · Crystal structure of bovine brain Ca++ calmodulin in a compact form · the same entry in another collection · chain A against A, TM-score 1.00
P62157 · AlphaFold monomer V2.0 prediction for calmodulin (P62157) · a predicted model of the same protein · chain A against A, TM-score 0.46

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P62157
Elsewhere: RCSB PDB 1PRW · PDBe 1PRW · UniProt P62157

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.