E.COLI'S putrescine receptor variant POTF/D (4JDF) with mutations E39D Y87S F88Y S247D in complex with spermidine

Structure

x-ray diffraction · 1 distinct chain.

Ligands and binding sites

• 3IE · (2~{S})-1-methoxypropan-2-amine · ligand · 5 copies · chains A, B
• SPD · Spermidine · ligand · 2 copies · chains A, B
• 4SW · (2~{S})-1-[(2~{R})-1-(2-methoxyethoxy)propan-2-yl]oxypropan-2-amine · ligand · chains A
• 4RH · (2~{R})-1-(2-methoxyethoxy)propan-2-amine · ligand · chains B
• 3IK · (2~{R})-1-[(2~{R})-1-[(2~{S})-1-[(2~{S})-1-(2-methoxyethoxy)propan-2-yl]oxypropan-2-yl]oxypropan-2-yl]oxypropan-2-amine · ligand · chains B
• ONT · (2~{S})-1-(2-methoxyethoxy)propan-2-amine · ligand · chains A, B
• CL · Chloride ion · ion · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 7OYX · E.coli's putrescine receptor variant PotF/D (4JDF) with mutations E39D Y87S F88Y S247D in… · the same entry in another collection · chain A against A, TM-score 1.00
• P31133 · AlphaFold monomer V2.0 prediction for putrescine-binding periplasmic protein potf (P31133) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P31133
• Elsewhere: RCSB PDB 7OYX · PDBe 7OYX · UniProt P31133