Research workbench
Apo-structure of lassa virus L protein (well-resolved alpha ribbon) [apo-ribbon]
Analyse Apo-structure of lassa virus L protein (well-resolved alpha ribbon) [apo-ribbon] in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7OE7
- Type
- protein
- Length
- 1,382 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA-directed RNA polymerase L
- EC
- 2.7.7.48, 3.1.-.-
- UniProt
- A0A3S8NV63
- Ligands
- ZN, MG
- Pockets
- 20 · best druggability 0.73
Structure
electron microscopy · 1 distinct chain · 46% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| L | RNA-directed RNA polymerase L (EC 2.7.7.48, 3.1.-.-) | protein | 1382 | 46% helix, 8% strand | A0A3S8NV63 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
20 pockets found on a 1 Å grid, 16 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1035 | 0.73 | 0.76 | 89 | empty |
| 2 | 56 | 0.72 | 0.98 | 19 | empty |
| 3 | 172 | 0.67 | 0.86 | 26 | empty |
| 4 | 662 | 0.67 | 0.76 | 69 | MG |
| 5 | 338 | 0.65 | 0.80 | 55 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 7OE7 · Apo-structure of Lassa virus L protein (well-resolved alpha ribbon) [APO-RIBBON] · the same entry in another collection · chain L against L, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A3S8NV63
- Elsewhere: RCSB PDB 7OE7 · PDBe 7OE7 · UniProt A0A3S8NV63
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