UniProt A0A3S8NV63
RNA-directed RNA polymerase L (A0A3S8NV63)
RNA-directed RNA polymerase L (UniProt A0A3S8NV63), EC 2.7.7.48, 3.1.-.-: 18 experimental structures on GenesisL1, 4 ligands bound, 158 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A3S8NV63
- Protein
- RNA-directed RNA polymerase L
- EC
- 2.7.7.48, 3.1.-.-
- Experimental structures
- 18
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 158 · 8 records with a druggable one
Structures
18 records of A0A3S8NV63 in the MolNFT archive: 18 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7OCH | Apo-structure of Lassa virus L protein (well-resolved polymerase core) [APO-CORE] | electron microscopy | L | ZN, MG | 20 (best 0.72) |
| 7OCH | Apo-structure of lassa virus L protein (well-resolved polymerase core) [apo-core] | electron microscopy | L | ZN, MG | — |
| 7OE3 | Apo-structure of Lassa virus L protein (well-resolved endonuclease) [APO-ENDO] | electron microscopy | L | ZN, MG | 20 (best 0.78) |
| 7OE3 | Apo-structure of lassa virus L protein (well-resolved endonuclease) [apo-endo] | electron microscopy | L | ZN, MG | — |
| 7OE7 | Apo-structure of Lassa virus L protein (well-resolved alpha ribbon) [APO-RIBBON] | electron microscopy | L | ZN, MG | — |
| 7OE7 | Apo-structure of lassa virus L protein (well-resolved alpha ribbon) [apo-ribbon] | electron microscopy | L | ZN, MG | — |
| 7OEA | Lassa virus L protein bound to 3' promoter RNA (well-resolved polymerase core) [3END-CORE] | electron microscopy | L | ZN, MG | 20 (best 0.71) |
| 7OEA | Lassa virus L protein bound to 3' promoter RNA (well-resolved polymerase core) [3END-core] | electron microscopy | L | ZN, MG | — |
| 7OEB | Lassa virus L protein bound to 3' promoter RNA (well-resolved endonuclease) [3END-ENDO] | electron microscopy | L | ZN, MG | 20 (best 0.74) |
| 7OEB | Lassa virus L protein bound to 3' promoter RNA (well-resolved endonuclease) [3END-endo] | electron microscopy | L | ZN, MG | — |
| 7OJJ | Lassa virus L protein with endonuclease and C-terminal domains in close proximity [MID-LINK] | electron microscopy | L | ZN, MG | 20 (best 0.78) |
| 7OJJ | Lassa virus L protein with endonuclease and C-terminal domains in close proximity [mid-link] | electron microscopy | L | ZN, MG | — |
| 7OJK | Lassa virus L protein bound to the distal promoter duplex [DISTAL-PROMOTER] | electron microscopy | L | ZN | 20 (best 0.74) |
| 7OJK | Lassa virus L protein bound to the distal promoter duplex [distal- promoter] | electron microscopy | L | ZN | — |
| 7OJL | Lassa virus L protein in a pre-initiation conformation [PREINITIATION] | electron microscopy | L | MN | 18 (best 0.75) |
| 7OJL | Lassa virus L protein in a pre-initiation conformation [preinitiation] | electron microscopy | L | MN | — |
| 7OJN | Lassa virus L protein in an elongation conformation [ELONGATION] | electron microscopy | L | 2KH, MN, ZN | 20 (best 0.84) |
| 7OJN | Lassa virus L protein in an elongation conformation [elongation] | electron microscopy | L | 2KH, MN, ZN | — |
Ligands
Elsewhere
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