Research workbench
Crystal structure of homo sapiens NUP93 solenoid (residues 174-819)
Analyse Crystal structure of homo sapiens NUP93 solenoid (residues 174-819) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7MW0
- Type
- protein
- Length
- 624 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nuclear pore complex protein NUP93
- UniProt
- Q8N1F7
- Pockets
- 5 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 65% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nuclear pore complex protein NUP93 | protein | 624 | 65% helix, 3% strand | Q8N1F7 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 106 | 0.53 | 0.83 | 22 | empty |
| 2 | 139 | 0.45 | 0.76 | 19 | empty |
| 3 | 115 | 0.43 | 0.77 | 24 | empty |
| 4 | 101 | 0.41 | 0.77 | 18 | empty |
| 5 | 91 | 0.37 | 0.76 | 24 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 7MW0 · Crystal structure of Homo sapiens NUP93 solenoid (residues 174-819) · the same entry in another collection · chain A against A, TM-score 1.00
- Q8N1F7 · AlphaFold monomer V2.0 prediction for nuclear pore complex protein NUP93 (Q8N1F7) · a predicted model of the same protein · chain A against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8N1F7
- Elsewhere: RCSB PDB 7MW0 · PDBe 7MW0 · UniProt Q8N1F7
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