MolNFT v1 · #277439 · protein

AlphaFold monomer V2.0 prediction for nuclear pore complex protein NUP93 (Q8N1F7)

Q8N1F7: “AlphaFold monomer V2.0 prediction for nuclear pore complex protein NUP93 (Q8N1F7)”. 11 pockets (best druggability 0.67). MolNFT v1 #277439 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q8N1F7
Type: protein
Length: 819 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x725C00D6BECAAdFa5C549918247063dBD4b20d2C
Molecule: Nuclear pore complex protein NUP93
UniProt: Q8N1F7
Pockets: 11 · best druggability 0.67

Structure

1 distinct chain · 65% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nuclear pore complex protein NUP93	protein	819	65% helix, 2% strand	Q8N1F7

Pockets

11 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	627	0.67	0.76	59	empty
2	83	0.57	0.88	16	empty
3	126	0.48	0.79	19	empty
4	85	0.48	0.83	14	empty
5	65	0.44	0.82	15	empty

Compared structures

7R5K · Human nuclear pore complex (constricted) · an experimental structure of the same protein · chain A against A1, TM-score 0.83
7R5J · Human nuclear pore complex (dilated) · an experimental structure of the same protein · chain A against A1, TM-score 0.82

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8N1F7
Elsewhere: UniProt Q8N1F7 · AlphaFold DB Q8N1F7

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