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Solution structure of berberine bound to a dgmp fill-in G-quadruplex in the pdgfr-B promoter

Analyse Solution structure of berberine bound to a dgmp fill-in G-quadruplex in the… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7MSV
Type
DNA
Length
19 nucleotides
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
DNA (5'- D(*AP*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*GP*CP*GP*GP*GP*AP*CP*A)-3')
Ligands
BER, DGP

Structure

solution nmr · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
XDNA (5'- D(*AP*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*GP*CP*GP*GP*GP*AP*CP*A)-3')dna19——

Ligands and binding sites

  • BER · Berberine · ligand · 2 copies · chains X
  • DGP · 2'-deoxyguanosine-5'-monophosphate · ligand · chains X

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7MSV · Solution Structure of Berberine Bound to a dGMP Fill-in G-Quadruplex in the PDGFR-b… · the same entry in another collection · chain X against X, TM-score 1.00

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