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T4 lysozyme mutant L99A in complex with 1-fluoro-2-[(prop-2-en-1-yl) OXY]BENZENE

Analyse T4 lysozyme mutant L99A in complex with 1-fluoro-2-[(prop-2-en-1-yl) OXY]BENZENE in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7LOB
Type: protein
Length: 162 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lysozyme
EC: 3.2.1.17
UniProt: D9IEF7
Ligands: ZNV
Pockets: 1 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 63% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lysozyme (EC 3.2.1.17)	protein	162	63% helix, 9% strand	D9IEF7

Ligands and binding sites

ZNV · 1-fluoro-2-[(prop-2-en-1-yl)oxy]benzene · ligand · chains A
BME · Beta-mercaptoethanol · additive · chains A
TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	287	0.55	0.76	31	BME, TRS

Compared structures

7LOB · T4 lysozyme mutant L99A in complex with 1-fluoro-2-[(prop-2-en-1-yl)oxy]benzene · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt D9IEF7
Elsewhere: RCSB PDB 7LOB · PDBe 7LOB · UniProt D9IEF7

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