Research workbench

5-ht bound serotonin transporter reconstituted in lipid nanodisc in kcl

Analyse 5-ht bound serotonin transporter reconstituted in lipid nanodisc in kcl in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7LI9
Type: protein
Length: 767 residues
Chains: 3
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P31645
Ligands: D10, D12, HP6, SRO, LNK, NAG, CL

Structure

electron microscopy · 3 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	539	—	P31645
B	—	protein	118	—	—
C	—	protein	110	—	—

Ligands and binding sites

D10 · Decane · ligand · 3 copies · chains A
D12 · Dodecane · ligand · 2 copies · chains A
HP6 · Heptane · ligand · 2 copies · chains A
SRO · Serotonin · ligand · 2 copies · chains A
LNK · Pentane · ligand · chains A
NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A
CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7LI9 · 5-HT bound serotonin transporter reconstituted in lipid nanodisc in KCl · the same entry in another collection · chain A against A, TM-score 1.00
P31645 · AlphaFold monomer V2.0 prediction for sodium-dependent serotonin transporter (P31645) · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P31645
Elsewhere: RCSB PDB 7LI9 · PDBe 7LI9 · UniProt P31645

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