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Crystal structure of haemophilus influenzae mtsz at pH 5.5

Analyse Crystal structure of haemophilus influenzae mtsz at pH 5.5 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7L5S
Type: protein
Length: 771 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Trimethylamine-N-oxide reductase
EC: 1.7.2.3
UniProt: A0A2S9RK57
Ligands: MGD, MO, O
Pockets: 4 · best druggability 0.86

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Trimethylamine-N-oxide reductase (EC 1.7.2.3)	protein	771	33% helix, 20% strand	A0A2S9RK57

Ligands and binding sites

MGD · 2-amino-5,6-dimercapto-7-methyl-3,7,8A,9-tetrahydro-8-oxa-1,3,9,10-tetraaza-anthracen-4-one guanosine dinucleotide · ligand · 2 copies · chains A
MO · Molybdenum atom · metal · chains A
O · Oxygen atom · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	761	0.86	0.89	104	O, MGD, MO
2	133	0.51	0.80	22	empty
3	137	0.46	0.77	21	empty
4	85	0.38	0.76	18	empty

Compared structures

7L5S · Crystal Structure of Haemophilus influenzae MtsZ at pH 5.5 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A2S9RK57
Elsewhere: RCSB PDB 7L5S · PDBe 7L5S · UniProt A0A2S9RK57

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