Research workbench
Cryogenic electron microscopy model of full-length human metavinculin H1' kinked conformation
Analyse Cryogenic electron microscopy model of full-length human metavinculin H1'… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7KTV
- Type
- protein
- Length
- 995 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Metavinculin
- UniProt
- P18206
- Pockets
- 14 · best druggability 0.85
Structure
electron microscopy · 1 distinct chain · 75% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Metavinculin | protein | 995 | 75% helix, 0% strand | P18206 |
Pockets
14 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 932 | 0.85 | 0.86 | 105 | empty |
| 2 | 530 | 0.83 | 0.89 | 84 | empty |
| 3 | 285 | 0.76 | 0.88 | 35 | empty |
| 4 | 100 | 0.75 | 0.95 | 30 | empty |
| 5 | 508 | 0.73 | 0.81 | 52 | empty |
Compared structures
- 7KTV · Cryogenic electron microscopy model of full-length human metavinculin H1' kinked… · the same entry in another collection · chain A against A, TM-score 1.00
- P18206 · AlphaFold monomer V2.0 prediction for vinculin (P18206) · a predicted model of the same protein · chain A against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P18206
- Elsewhere: RCSB PDB 7KTV · PDBe 7KTV · UniProt P18206
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