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Cryogenic electron microscopy model of full-length human metavinculin

Analyse Cryogenic electron microscopy model of full-length human metavinculin in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7KTT
Type: protein
Length: 994 residues
Chains: 1
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Metavinculin
UniProt: P18206
Pockets: 16 · best druggability 0.80

Structure

electron microscopy · 1 distinct chain · 76% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Metavinculin	protein	994	76% helix, 0% strand	P18206

Pockets

16 pockets found on a 1 Å grid, 12 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	621	0.80	0.86	88	empty
2	303	0.78	0.89	32	empty
3	143	0.77	0.94	27	empty
4	77	0.71	0.95	24	empty
5	131	0.69	0.90	37	empty

Compared structures

7KTT · Cryogenic electron microscopy model of full-length human metavinculin · the same entry in another collection · chain A against A, TM-score 1.00
P18206 · AlphaFold monomer V2.0 prediction for vinculin (P18206) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P18206
Elsewhere: RCSB PDB 7KTT · PDBe 7KTT · UniProt P18206

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