Research workbench
Yersinia protein-tyrosine phosphatase complexed with pncs (YOP51, pasteurella X,PTPASE,YOP51DELTA162) (catalytic domain, residues 163- 468) mutant with cys 235 replaced by arg (C235R)
Analyse Yersinia protein-tyrosine phosphatase complexed with pncs (YOP51, pasteurella… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1PA9
- Type
- protein
- Length
- 279 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein-tyrosine phosphatase yoph
- EC
- 3.1.3.48
- UniProt
- P15273
- Ligands
- CSN
- Pockets
- 1 · best druggability 0.39
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein-tyrosine phosphatase yoph (EC 3.1.3.48) | protein | 279 | 38% helix, 21% strand | P15273 |
Ligands and binding sites
- CSN · N,4-dihydroxy-N-oxo-3-(sulfooxy)benzenaminium · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 100 | 0.39 | 0.76 | 19 | empty |
Compared structures
- 1PA9 · Yersinia Protein-Tyrosine Phosphatase complexed with pNCS (Yop51,Pasteurella… · the same entry in another collection · chain A against A, TM-score 1.00
- P15273 · AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase yoph (P15273) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P15273
- Elsewhere: RCSB PDB 1PA9 · PDBe 1PA9 · UniProt P15273
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