Research workbench
Beta hairpin derived from ABETA17-36 with an F20CHA mutation
Analyse Beta hairpin derived from ABETA17-36 with an F20CHA mutation in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7JXN
- Type
- protein
- Length
- 84 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Amyloid-beta 17-36 peptide
- UniProt
- P05067
- Ligands
- NA, CL
Structure
x-ray diffraction · 1 distinct chain · 0% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | Amyloid-beta 17-36 peptide | protein | 21 | 0% helix, 38% strand | P05067 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
2 interfaces between chains.
- B–C · 298 Ų buried · 3 hydrogen bonds · protein-protein
- A–D · 271 Ų buried · 2 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 12 modified (nonstandard).
Compared structures
- 7JXN · Beta hairpin derived from Abeta17-36 with an F20Cha mutation · the same entry in another collection · chain D against D, TM-score 1.00
- P05067 · AlphaFold monomer V2.0 prediction for amyloid-beta precursor protein (P05067) · a predicted model of the same protein · chain D against A, TM-score 0.30
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P05067
- Elsewhere: RCSB PDB 7JXN · PDBe 7JXN · UniProt P05067
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