Research workbench
Crystal structure of TAF14 yeats domain in complex with H3K9BZ peptide
Analyse Crystal structure of TAF14 yeats domain in complex with H3K9BZ peptide in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7F4A
- Type
- protein
- Length
- 141 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcription initiation factor tfiid subunit 14; Histone H3
- UniProt
- P35189, P61830
- Ligands
- ACE
Structure
x-ray diffraction · 2 distinct chains · 7% helix, 53% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcription initiation factor tfiid subunit 14 | protein | 136 | 7% helix, 54% strand | P35189 |
| B | Histone H3 | protein | 5 | 0% helix, 20% strand | P61830 |
Ligands and binding sites
- ACE · Acetyl group · ligand · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 515 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 covalent, 1 modified (covalent ligand, nonstandard).
Compared structures
- 7F4A · Crystal structure of Taf14 YEATS domain in complex with H3K9bz peptide · the same entry in another collection · chain A against A, TM-score 1.00
- P35189 · AlphaFold monomer V2.0 prediction for transcription initiation factor tfiid subunit 14… · a predicted model of the same protein · chain A against A, TM-score 0.99
- P61830 · AlphaFold monomer V2.0 prediction for histone H3 (P61830) · a predicted model of the same protein · chain B against A, TM-score 0.59
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P35189
- Every structure of UniProt P61830
- Elsewhere: RCSB PDB 7F4A · PDBe 7F4A · UniProt P35189 · UniProt P61830
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