UniProt P61830
Histone H3 (P61830)
Histone H3 (UniProt P61830): 42 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 22 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P61830
- Protein
- Histone H3
- Experimental structures
- 42
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 22 · 6 records with a druggable one
Structures
43 records of P61830 in the MolNFT archive: 42 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ID3 | Crystal structure of the yeast nucleosome core particle reveals fundamental differences in… | x-ray diffraction | A, E | — | — |
| 1ID3 | Crystal structure of the yeast nucleosome core particle reveals fundamental differences in… | x-ray diffraction | A, E | — | — |
| 1QSN | Crystal structure of tetrahymena GCN5 with bound coenzyme a and histone H3 peptide | x-ray diffraction | B | — | — |
| 1QSN | Crystal structure of tetrahymena GCN5 with bound coenzyme a and histone H3 peptide | x-ray diffraction | B | — | — |
| 2H2G | The Structural Basis of Sirtuin substrate affinity | x-ray diffraction | B | — | — |
| 2H2G | The structural basis of sirtuin substrate affinity | x-ray diffraction | B | — | — |
| 2IDC | Structure of the Histone H3-Asf1 Chaperone Interaction | x-ray diffraction | A | — | — |
| 2IDC | Structure of the histone H3-ASF1 chaperone interaction | x-ray diffraction | A | — | — |
| 2JMJ | NMR solution structure of the PHD domain from the yeast YNG1 protein in complex with H3(1-9)K4me3… | solution nmr | P | — | — |
| 2JMJ | NMR solution structure of the phd domain from the yeast YNG1 protein in complex with H3(1-9)K4ME3… | solution nmr | P | — | — |
| 2RNW | The Structural Basis for Site-Specific Lysine-Acetylated Histone Recognition by the Bromodomains of… | solution nmr | B | — | — |
| 2RNW | The structural basis for site-specific lysine-acetylated histone recognition by the bromodomains of… | solution nmr | B | — | — |
| 2RNX | The Structural Basis for Site-Specific Lysine-Acetylated Histone Recognition by the Bromodomains of… | solution nmr | B | — | — |
| 2RNX | The structural basis for site-specific lysine-acetylated histone recognition by the bromodomains of… | solution nmr | B | — | — |
| 3Q33 | Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone… | x-ray diffraction | D | — | — |
| 3Q33 | Structure of the RTT109-ACCOA/VPS75 complex and implications for chaperone-mediated histone… | x-ray diffraction | D | — | — |
| 4JJN | Crystal structure of heterochromatin protein Sir3 in complex with a silenced yeast nucleosome | x-ray diffraction | A, E | — | — |
| 4JJN | Crystal structure of heterochromatin protein SIR3 in complex with a silenced yeast nucleosome | x-ray diffraction | A, E | — | — |
| 4KUD | Crystal structure of N-terminal acetylated Sir3 BAH domain D205N mutant in complex with yeast… | x-ray diffraction | A, E | — | — |
| 4KUD | Crystal structure of N-terminal acetylated SIR3 bah domain D205N mutant in complex with yeast… | x-ray diffraction | A, E | — | — |
| 4PSX | Crystal structure of histone acetyltransferase complex | x-ray diffraction | Y, P | — | — |
| 4PSX | Crystal structure of histone acetyltransferase complex | x-ray diffraction | Y, P | — | — |
| 5ZBA | Crystal structure of RTT109-ASF1-H3-H4-CoA complex | x-ray diffraction | C | IOD | — |
| 5ZBB | Crystal structure of RTT109-ASF1-H3-H4 complex | x-ray diffraction | C | IOD | — |
| 6GEJ | Chromatin remodeller-nucleosome complex at 3.6 a resolution. | electron microscopy | A, B | — | — |
| 6GEN | Chromatin remodeller-nucleosome complex at 4.5 A resolution. | electron microscopy | A, B | — | 1 (best 0.73) |
| 6GEN | Chromatin remodeller-nucleosome complex at 4.5 a resolution. | electron microscopy | A, B | — | — |
| 6J2P | Crystal structure of saccharomyces cerevisiae SPP1 in complex with H3K4ME3 | x-ray diffraction | E, F, G, H | — | — |
| 6KMJ | Crystal structure of Sth1 bromodomain in complex with H3K14Ac | x-ray diffraction | C | — | — |
| 6KMJ | Crystal structure of STH1 bromodomain in complex with H3K14AC | x-ray diffraction | C | — | — |
| 7E9C | Cryo-EM structure of the 1:1 Orc1 BAH domain in complex with nucleosome | electron microscopy | A, E | — | 11 (best 0.83) |
| 7F4A | Crystal structure of TAF14 yeats domain in complex with H3K9BZ peptide | x-ray diffraction | B | ACE | — |
| 7F4E | Crystal structure of Hst2 in complex with H3K9bz peptide | x-ray diffraction | C | — | — |
| 7F4E | Crystal structure of HST2 in complex with H3K9BZ peptide | x-ray diffraction | C | — | — |
| 7K7G | Nucleosome and GAL4 complex | electron microscopy | A, E | — | — |
| 7UQJ | Cryo-EM structure of the S. cerevisiae chromatin remodeler Yta7 hexamer bound to ATPgS and histone… | electron microscopy | G | — | — |
| 7XAY | Crystal structure of Hat1-Hat2-Asf1-H3-H4 | x-ray diffraction | D | — | 4 (best 0.77) |
| 7XAY | Crystal structure of HAT1-HAT2-ASF1-H3-H4 | x-ray diffraction | D | — | — |
| 7Z0O | Structure of transcription factor uaf in complex with tbp and 35S rRNA promoter DNA | — | — | — | |
| 8QKV | SWR1-nucleosome complex in configuration 2 | electron microscopy | B, A | — | 1 (best 0.77) |
| 8QZ0 | SWR1-hexasome-dimer complex | electron microscopy | A, B | — | 3 (best 0.83) |
| 9FBW | SWR1 lacking Swc5 subunit in complex with hexasome | electron microscopy | A, B | — | 2 (best 0.82) |
| P61830 | AlphaFold monomer V2.0 prediction for histone H3 (P61830) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1ID3 chain A against the predicted model P61830: TM-score 0.99, RMSD 0.41 Å
- 1ID3 chain A against the predicted model P61830: TM-score 0.99, RMSD 0.41 Å
- 4JJN chain E against the predicted model P61830: TM-score 0.99, RMSD 0.45 Å
- 4JJN chain E against the predicted model P61830: TM-score 0.99, RMSD 0.45 Å
- 4KUD chain A against the predicted model P61830: TM-score 0.98, RMSD 0.45 Å
- 4KUD chain A against the predicted model P61830: TM-score 0.98, RMSD 0.45 Å
- 4KUD chain E against the predicted model P61830: TM-score 0.98, RMSD 0.48 Å
- 4KUD chain E against the predicted model P61830: TM-score 0.98, RMSD 0.48 Å
- 4JJN chain A against the predicted model P61830: TM-score 0.98, RMSD 0.55 Å
- 4JJN chain A against the predicted model P61830: TM-score 0.98, RMSD 0.55 Å
Elsewhere
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