Crystal structure of L-cycloserine-bound form of cysteine desulfurase sufs C361A from bacillus subtilis

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 18% strand (DSSP).

Ligands and binding sites

• 7TS · (5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate · ligand · chains A
• PEG · Di(hydroxyethyl)ether · additive · 10 copies · chains A
• EDO · 1,2-ethanediol · additive · 3 copies · chains A
• PG4 · Tetraethylene glycol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Compared structures

• 7E6C · Crystal structure of L-cycloserine-bound form of cysteine desulfurase SufS C361A from… · the same entry in another collection · chain A against A, TM-score 1.00
• O32164 · AlphaFold monomer V2.0 prediction for cysteine desulfurase sufs (O32164) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt O32164
• Elsewhere: RCSB PDB 7E6C · PDBe 7E6C · UniProt O32164