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Structure of drosophila melanogaster glcnac-1-phosphotransferase

Analyse Structure of drosophila melanogaster glcnac-1-phosphotransferase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7DXI
Type: protein
Length: 742 residues
Chains: 2
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: FI02838P
UniProt: A1Z7S7
Ligands: CA
Pockets: 8 · best druggability 0.71

Structure

electron microscopy · 1 distinct chain · 37% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	FI02838P	protein	371	37% helix, 10% strand	A1Z7S7

Ligands and binding sites

CA · Calcium ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

8 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	568	0.71	0.79	55	empty
2	595	0.71	0.79	55	empty
3	155	0.54	0.80	26	empty
4	138	0.54	0.81	23	empty
5	132	0.52	0.81	21	empty

Interfaces

1 interface between chains.

A–B · 1618 Å² buried · 20 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

7DXI · Structure of Drosophila melanogaster GlcNAc-1-phosphotransferase · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A1Z7S7
Elsewhere: RCSB PDB 7DXI · PDBe 7DXI · UniProt A1Z7S7

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