Research workbench
Crystal structure of biotin protein ligase from leishmania major in complex with biotin
Analyse Crystal structure of biotin protein ligase from leishmania major in complex… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7DBS
- Type
- protein
- Length
- 252 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- BIOTIN/LIPOATE protein ligase-like protein
- EC
- 6.3.4.15
- UniProt
- Q4Q6F6
- Ligands
- BTN
- Pockets
- 2 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 29% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | BIOTIN/LIPOATE protein ligase-like protein (EC 6.3.4.15) | protein | 252 | 29% helix, 27% strand | Q4Q6F6 |
Ligands and binding sites
- BTN · Biotin · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 389 | 0.67 | 0.80 | 47 | BTN |
| 2 | 164 | 0.41 | 0.74 | 27 | empty |
Compared structures
- 7DBS · Crystal Structure Of Biotin Protein Ligase From Leishmania Major in complex with Biotin · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q4Q6F6
- Elsewhere: RCSB PDB 7DBS · PDBe 7DBS · UniProt Q4Q6F6
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.