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Human KCNQ2 in complex with ZTZ240

Analyse Human KCNQ2 in complex with ZTZ240 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7CR1
Type: protein
Length: 1,000 residues
Chains: 4
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: O43526
Ligands: GB9

Structure

electron microscopy · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D	—	protein	250	—	O43526

Ligands and binding sites

GB9 · N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide · ligand · 4 copies · chains A, B, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7CR1 · human KCNQ2 in complex with ztz240 · the same entry in another collection · chain A against A, TM-score 1.00
O43526 · AlphaFold monomer V2.0 prediction for potassium voltage-gated channel subfamily kqt… · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O43526
Elsewhere: RCSB PDB 7CR1 · PDBe 7CR1 · UniProt O43526

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