Research workbench
Crystal structure of rsmg methyltransferase of M. tuberculosis
Analyse Crystal structure of rsmg methyltransferase of M. tuberculosis in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7CFE
- Type
- protein
- Length
- 214 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ribosomal RNA small subunit methyltransferase G
- EC
- 2.1.1.-
- UniProt
- P9WGW9
- Ligands
- SFG, PO4
- Pockets
- 2 · best druggability 0.47
Structure
x-ray diffraction · 1 distinct chain · 47% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribosomal RNA small subunit methyltransferase G (EC 2.1.1.-) | protein | 214 | 47% helix, 22% strand | P9WGW9 |
Ligands and binding sites
- SFG · Sinefungin · ligand · chains A
- PO4 · Phosphate ion · ion · chains A
- IPA · Isopropyl alcohol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 143 | 0.47 | 0.77 | 27 | SFG |
| 2 | 73 | 0.27 | 0.71 | 17 | empty |
Compared structures
- 7CFE · Crystal structure of RsmG methyltransferase of M. tuberculosis · the same entry in another collection · chain A against A, TM-score 1.00
- P9WGW9 · AlphaFold monomer V2.0 prediction for ribosomal RNA small subunit methyltransferase G… · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P9WGW9
- Elsewhere: RCSB PDB 7CFE · PDBe 7CFE · UniProt P9WGW9
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