Research workbench

Escherichia COLI ytfe E125L

Analyse Escherichia COLI ytfe E125L in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7BHC
Type: protein
Length: 438 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Iron-sulfur cluster repair protein ytfe
UniProt: W8TAR7
Ligands: FE, O
Pockets: 5 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 71% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Iron-sulfur cluster repair protein ytfe	protein	219	71% helix, 1% strand	W8TAR7

Ligands and binding sites

FE · Fe (III) ion · metal · 4 copies · chains A, B
O · Oxygen atom · ion · 2 copies · chains A, B
GOL · Glycerol · additive · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	153	0.55	0.81	19	empty
2	307	0.54	0.75	41	empty
3	157	0.51	0.79	22	empty
4	140	0.48	0.78	22	empty
5	88	0.33	0.74	19	empty

Interfaces

1 interface between chains.

A–B · 94 Å² buried · 1 hydrogen bond · protein-protein

Compared structures

7BHC · Escherichia coli YtfE E125L · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt W8TAR7
Elsewhere: RCSB PDB 7BHC · PDBe 7BHC · UniProt W8TAR7

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.