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Escherichia COLI ytfe

Analyse Escherichia COLI ytfe in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7BHA
Type: protein
Length: 431 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Iron-sulfur cluster repair protein ytfe
UniProt: W8TAR7
Ligands: FE, O
Pockets: 6 · best druggability 0.56

Structure

x-ray diffraction · 2 distinct chains · 71% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Iron-sulfur cluster repair protein ytfe	protein	219	73% helix, 1% strand	W8TAR7
B	Iron-sulfur cluster repair protein ytfe	protein	212	69% helix, 0% strand	W8TAR7

Ligands and binding sites

FE · Fe (III) ion · metal · 4 copies · chains A, B
O · Oxygen atom · ion · 2 copies · chains A, B
GOL · Glycerol · additive · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	361	0.56	0.75	50	GOL
2	118	0.55	0.83	18	empty
3	153	0.55	0.81	17	empty
4	161	0.49	0.77	23	empty
5	62	0.39	0.80	14	empty

Interfaces

1 interface between chains.

A–B · 205 Å² buried · 1 hydrogen bond · protein-protein

Compared structures

7BHA · Escherichia coli YtfE · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt W8TAR7
Elsewhere: RCSB PDB 7BHA · PDBe 7BHA · UniProt W8TAR7

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