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3D electron diffraction structure of bovine insulin

Analyse 3D electron diffraction structure of bovine insulin in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6ZHB
Type: protein
Length: 99 residues
Chains: 4
Method: electron crystallography
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Insulin
UniProt: P01317
Ligands: ZN

Structure

electron crystallography · 3 distinct chains · 36% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, C	Insulin	protein	21	19% helix, 5% strand	P01317
B	Insulin	protein	28	39% helix, 14% strand	P01317
D	Insulin	protein	29	45% helix, 14% strand	P01317

Ligands and binding sites

ZN · Zinc ion · metal · chains D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

5 interfaces between chains.

A–B · 839 Å² buried · 6 hydrogen bonds · protein-protein
C–D · 760 Å² buried · 7 hydrogen bonds · protein-protein
B–D · 610 Å² buried · 6 hydrogen bonds · protein-protein
B–C · 54 Å² buried · 0 hydrogen bonds · protein-protein
A–D · 34 Å² buried · 0 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 disulfide (disulfide).

Compared structures

6ZHB · 3D electron diffraction structure of bovine insulin · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P01317
Elsewhere: RCSB PDB 6ZHB · PDBe 6ZHB · UniProt P01317

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