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Thalictrum flavumn norcoclaurine synthase point mutant in complex with a transition state analoge

Analyse Thalictrum flavumn norcoclaurine synthase point mutant in complex with a… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6Z82
Type: protein
Length: 159 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: S-norcoclaurine synthase
EC: 4.2.1.78
UniProt: Q67A25
Ligands: QBW
Pockets: 1 · best druggability 0.70

Structure

x-ray diffraction · 1 distinct chain · 25% helix, 42% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	S-norcoclaurine synthase (EC 4.2.1.78)	protein	159	25% helix, 42% strand	Q67A25

Ligands and binding sites

QBW · 4-[2-[(phenylmethyl)amino]ethyl]benzene-1,2-diol · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	211	0.70	0.86	33	QBW

Compared structures

6Z82 · Thalictrum flavumn Norcoclaurine synthase point mutant in complex with a transition state… · the same entry in another collection · chain A against A, TM-score 1.00
Q67A25 · AlphaFold monomer V2.0 prediction for S-norcoclaurine synthase (Q67A25) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q67A25
Elsewhere: RCSB PDB 6Z82 · PDBe 6Z82 · UniProt Q67A25

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