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Repulsive guidance molecule B (rgmb) in complex with growth differentiation factor 5 (GDF5) (crystal form 2)

Analyse Repulsive guidance molecule B (rgmb) in complex with growth differentiation… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
6Z3H
Type
protein
Length
161 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
GROWTH/DIFFERENTIATION factor 5; Rgm domain family member B
UniProt
P43026, Q6NW40

Structure

x-ray diffraction · 2 distinct chains · 30% helix, 29% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AGROWTH/DIFFERENTIATION factor 5protein10511% helix, 45% strandP43026
BRgm domain family member Bprotein5664% helix, 0% strandQ6NW40

Interfaces

1 interface between chains.

  • A–B · 443 Ų buried · 2 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 disulfide (disulfide).

Compared structures

  • 6Z3H · Repulsive Guidance Molecule B (RGMB) in complex with Growth Differentiation Factor 5… · the same entry in another collection · chain A against A, TM-score 1.00
  • P43026 · AlphaFold monomer V2.0 prediction for GROWTH/DIFFERENTIATION factor 5 (P43026) · a predicted model of the same protein · chain A against A, TM-score 0.96
  • Q6NW40 · AlphaFold monomer V2.0 prediction for rgm domain family member B (Q6NW40) · a predicted model of the same protein · chain B against A, TM-score 0.91

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