Research workbench
ASPARTYL/ASPARAGINYL beta-hydroxylase (asph) oxygenase and tpr domains in complex with manganese and 2-oxoglutarate
Analyse ASPARTYL/ASPARAGINYL beta-hydroxylase (asph) oxygenase and tpr domains in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6YYU
- Type
- protein
- Length
- 427 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ASPARTYL/ASPARAGINYL beta-hydroxylase
- EC
- 1.14.11.16
- UniProt
- Q12797
- Ligands
- AKG, MN
- Pockets
- 1 · best druggability 0.63
Structure
x-ray diffraction · 1 distinct chain · 53% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | ASPARTYL/ASPARAGINYL beta-hydroxylase (EC 1.14.11.16) | protein | 427 | 53% helix, 16% strand | Q12797 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 242 | 0.63 | 0.81 | 42 | MN, AKG |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 6YYU · Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
- Q12797 · AlphaFold monomer V2.0 prediction for ASPARTYL/ASPARAGINYL beta- hydroxylase (Q12797) · a predicted model of the same protein · chain A against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12797
- Elsewhere: RCSB PDB 6YYU · PDBe 6YYU · UniProt Q12797
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