Research workbench
Crystal structure of the tetramerization domain of the glycoprotein gn (andes virus) at pH 7.5
Analyse Crystal structure of the tetramerization domain of the glycoprotein gn (andes… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6YRB
- Type
- protein + RNA
- Length
- 205 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Envelope polyprotein; RNA (5'-D(*())-R(P*UP*UP*UP*())-3')
- UniProt
- Q9E006
- Ligands
- NAG, BMA, FUC, IOD
Structure
x-ray diffraction · 3 distinct chains · 25% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Envelope polyprotein | protein | 100 | 25% helix, 41% strand | Q9E006 |
| B | Envelope polyprotein | protein | 99 | 25% helix, 42% strand | Q9E006 |
| C, D | RNA (5'-D(*())-R(P*UP*UP*UP*())-3') | rna | 3 | — | — |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A
- BMA · beta-D-mannopyranose · sugar
- FUC · alpha-L-fucopyranose · sugar · chains A
- IOD · Iodide ion · ion · 6 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
2 interfaces between chains.
- B–C · 456 Ų buried · 12 hydrogen bonds · protein-nucleic
- A–D · 438 Ų buried · 10 hydrogen bonds · protein-nucleic
Modifications
Observed in the structure: 8 disulfide, 1 glycan (disulfide, N-glycosylation).
Compared structures
- 6YRB · Crystal structure of the tetramerization domain of the glycoprotein Gn (Andes virus) at… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9E006
- Elsewhere: RCSB PDB 6YRB · PDBe 6YRB · UniProt Q9E006
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.