Beta-phosphoglucomutase from lactococcus lactis with citrate, tris and acetate bound

Structure

x-ray diffraction · 1 distinct chain · 53% helix, 11% strand (DSSP).

Ligands and binding sites

• MG · Magnesium ion · metal · 2 copies · chains A, B
• ACT · Acetate ion · additive · 2 copies · chains A, B
• CIT · Citric acid · additive · chains A
• PDO · 1,3-propandiol · additive · chains A
• TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains B
• EDO · 1,2-ethanediol · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Interfaces

1 interface between chains.

• A–B · 577 Ų buried · 5 hydrogen bonds · protein-protein

Compared structures

• 6YDM · beta-phosphoglucomutase from Lactococcus lactis with citrate, tris and acetate bound · the same entry in another collection · chain A against A, TM-score 1.00
• P71447 · AlphaFold monomer V2.0 prediction for beta-phosphoglucomutase (P71447) · a predicted model of the same protein · chain A against A, TM-score 0.87

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P71447
• Elsewhere: RCSB PDB 6YDM · PDBe 6YDM · UniProt P71447