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An inactive (D136N and D137N) variant of alpha-1,6-mannanase, GH76A of salegentibacter sp. HEL1_6 in complex with alpha-1,6-mannotriose
Analyse An inactive (D136N and D137N) variant of alpha-1,6-mannanase, GH76A of… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6Y8F
- Type
- protein
- Length
- 338 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Alpha-1,6-endo-mannanase GH76A mutant
- Ligands
- MAN, CA
- Pockets
- 2 · best druggability 0.54
Structure
x-ray diffraction · 1 distinct chain · 63% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Alpha-1,6-endo-mannanase GH76A mutant | protein | 338 | 63% helix, 8% strand | — |
Ligands and binding sites
- MAN · alpha-D-mannopyranose · sugar · 3 copies · chains A
- CA · Calcium ion · metal · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 156 | 0.54 | 0.80 | 26 | empty |
| 2 | 113 | 0.42 | 0.76 | 19 | MAN |
Compared structures
- 6Y8F · An inactive (D136N and D137N) variant of alpha-1,6-mannanase, GH76A of Salegentibacter… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6Y8F · PDBe 6Y8F
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