Fucosylated antimicrobial linear peptide CFUCRH46D in complex with the fucose binding lectin lecb from pseudomonas aeruginosa at 2.1 ångström resolution

Structure

x-ray diffraction · 2 distinct chains · 9% helix, 64% strand (DSSP).

Ligands and binding sites

• ZDC · 3,7-anhydro-2,8-dideoxy-L-glycero-D-gluco-octonic acid · sugar · 2 copies · chains A, C, B, D
• CA · Calcium ion · metal · 4 copies · chains A, B
• NH2 · Amino group · ion · 2 copies · chains C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

3 interfaces between chains.

• A–B · 1326 Ų buried · 21 hydrogen bonds · protein-protein
• B–D · 151 Ų buried · 1 hydrogen bond · protein-protein
• A–C · 144 Ų buried · 1 hydrogen bond · protein-protein

Modifications

Observed in the structure: 26 d-amino, 2 glycan (D-amino acid, glycosylation).

Compared structures

• 6Y0W · Fucosylated antimicrobial linear peptide cFucRH46D in complex with the fucose binding… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt A0A069Q9V4
• Elsewhere: RCSB PDB 6Y0W · PDBe 6Y0W · UniProt A0A069Q9V4