Research workbench
Structure of glutamate transporter homologue glttk in unsaturated conditions - outward-outward-inward configuration
Analyse Structure of glutamate transporter homologue glttk in unsaturated conditions… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6XWP
- Type
- protein
- Length
- 1,278 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- PROTON/GLUTAMATE symporter, sdf family
- UniProt
- Q5JID0
- Ligands
- ASP
- Pockets
- 14 · best druggability 0.88
Structure
electron microscopy · 1 distinct chain · 74% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | PROTON/GLUTAMATE symporter, sdf family | protein | 426 | 74% helix, 0% strand | Q5JID0 |
Ligands and binding sites
- ASP · Aspartic acid · ligand · 2 copies · chains B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
14 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 535 | 0.88 | 0.92 | 39 | empty |
| 2 | 642 | 0.65 | 0.75 | 61 | empty |
| 3 | 612 | 0.65 | 0.75 | 64 | empty |
| 4 | 150 | 0.56 | 0.82 | 26 | empty |
| 5 | 256 | 0.51 | 0.75 | 47 | empty |
Interfaces
3 interfaces between chains.
- B–C · 1193 Ų buried · 13 hydrogen bonds · protein-protein
- A–C · 1177 Ų buried · 8 hydrogen bonds · protein-protein
- A–B · 1171 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 6XWP · Structure of glutamate transporter homologue GltTk in unsaturated conditions… · the same entry in another collection · chain C against C, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5JID0
- Elsewhere: RCSB PDB 6XWP · PDBe 6XWP · UniProt Q5JID0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.