Research workbench
Crystal structure of an otu deubiquitinase from escherichia albertii bound to ubiquitin
Analyse Crystal structure of an otu deubiquitinase from escherichia albertii bound to… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6W9S
- Type
- protein
- Length
- 255 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Otu domain-containing protein eschotu; Ubiquitin
- UniProt
- B1EF49, P0CG48
- Ligands
- NEH
- Pockets
- 1 · best druggability 0.59
Structure
x-ray diffraction · 2 distinct chains · 42% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Otu domain-containing protein eschotu | protein | 178 | 50% helix, 10% strand | B1EF49 |
| B | Ubiquitin | protein | 77 | 25% helix, 34% strand | P0CG48 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 283 | 0.59 | 0.78 | 24 | empty |
Interfaces
1 interface between chains.
- A–B · 895 Ų buried · 18 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 covalent (covalent ligand).
Compared structures
- 6W9S · Crystal structure of an OTU deubiquitinase from Escherichia albertii bound to ubiquitin · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B1EF49
- Every structure of UniProt P0CG48
- Elsewhere: RCSB PDB 6W9S · PDBe 6W9S · UniProt B1EF49 · UniProt P0CG48
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.