Research workbench
N-acetylmannosamine-6-phosphate 2-epimerase from staphylococcus aureus (strain mrsa USA300)
Analyse N-acetylmannosamine-6-phosphate 2-epimerase from staphylococcus aureus (strain… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6VVA
- Type
- protein
- Length
- 444 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- N-acetylmannosamine-6-phosphate 2-epimerase
- EC
- 5.1.3.9
- UniProt
- X5EM89
- Ligands
- CL
- Pockets
- 3 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9) | protein | 222 | 41% helix, 17% strand | X5EM89 |
Ligands and binding sites
- CL · Chloride ion · ion · 2 copies · chains A, B
- CIT · Citric acid · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 322 | 0.60 | 0.78 | 47 | empty |
| 2 | 224 | 0.60 | 0.80 | 23 | CIT |
| 3 | 230 | 0.59 | 0.80 | 24 | CIT |
Interfaces
1 interface between chains.
- A–B · 485 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 6VVA · N-Acetylmannosamine-6-phosphate 2-epimerase from Staphylococcus aureus (strain MRSA… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt X5EM89
- Elsewhere: RCSB PDB 6VVA · PDBe 6VVA · UniProt X5EM89
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