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Solution structure of the ttd and linker region of mouse UHRF1 (NP95)

Analyse Solution structure of the ttd and linker region of mouse UHRF1 (NP95) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6VEE
Type: protein
Length: 184 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: E3 ubiquitin-protein ligase UHRF1
EC: 2.3.2.27
UniProt: Q8VDF2
Pockets: 1 · best druggability 0.28

Structure

solution nmr · 1 distinct chain · 5% helix, 40% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27)	protein	184	5% helix, 40% strand	Q8VDF2

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	60	0.28	0.74	15	empty

Compared structures

6VEE · Solution structure of the TTD and linker region of mouse UHRF1 (NP95) · the same entry in another collection · chain A against A, TM-score 1.00
Q8VDF2 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase UHRF1 (Q8VDF2) · a predicted model of the same protein · chain A against A, TM-score 0.69

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8VDF2
Elsewhere: RCSB PDB 6VEE · PDBe 6VEE · UniProt Q8VDF2

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